5-MeO-MiPT – Discovery, History & Research
The Discover of 5-MeO-MiPT is cited as being first discussed by in a paper published in 1985 by a team led by the famous Alexander Shulgin.
Since its first publication of synthesis in 1985, 5-MeO-MiPT does not seem to have any history of human usage other than some toxicology reports and some papers discussion the online psychoactive use of “designer drugs”. After some initial availability in the research chemical boom between 2009 and 2016, 5-MeO-MiPT was made illegal in many countries under various laws. Notably, in the UK, USA and China.
Research into 5-MeO-MiPT has revolved predominantly around its discussion as an online “designer drug” utilised as a “legal high” and so the publications (other than some early synthesis papers) revolve arouns the toxicology and illicit use online. There has been some research into the receptor binding of 5-MeO-MiPT.
Some of these papers are listed below.
5-MeO-MiPT – Chemical Structural Data
5-MeO-MiPT is a synthetic indole alkaloid molecule withing the broader tryptamine class of compound. The key principle within it’s Tryptamine family is the core, which comprises a bicyclic idole heterocycle with a R3 attached to the amino group via an ethyl chain. However, with 5-MeO-MiPT, there is a methoxy (MeO) group which has been substituted at the R5 with another methyl and isopropyl chain bound to its terminal amino. 5-MeO-MiPT is technically the substituted isopropyl homologue of 5-MeO-DMT.
5-MeO-MiPT – Structure-Activity & Chemical Similarity Predictions
Based on the knows receptor profiling we’ve seen with the closer chemical analogues such as 5-MeO-DMT, 5-MeO-DiPT, DiPT, and MiPT. It would be fair to assume that 5-MeO-MiPT act as a psychedelic and entactogen much like other Tryptamines with it’s efficacy coming, primarily from its affinity for the 5-HT2A receptor as a partial agonis. There may also be some action on the MAO pathway.
Key Areas of Research
Samples of 5-MeO-MiPT to purchase online may be used in the following scientific applications.
As a forensic sample and/or for forensic chemical catalogues.
As a reference sample for Toxicology laboratories.
As a chemical reagent and/or intermediate
As a research chemical sample within studying pharmacology of receptor binding assays.
Affinity and Efficacy Receptor profiling for the Seretonin and MAO receptor groups.
Reference sample for the application within future therapeutic compounds
Pure reference standard for chemical analytical libraries using HPLC, FTIR, NMR and GC/MS equipment
5-MeO-MiPT – Online Anecdotal Reports
Since it became relatively easy for customer to order 5-MeO-MiPT online in the USA and gain knowledge of its action via vendor information and Pychonaut website, there has been a lot of discussion.
The main focus of discussion is always of its anecdotal use on forum such as Reddit and Erowid, with posts detailing 5-MeO-MiPT dosage, legal status experience and much more.
Forum links to anecdotal discussion by those who are able to buy 5-MeO-MiPT HCL online.
Chemical Safety, Legality & Indented Use
This is a research chemical compound. Sold as an analytical standard, reagent or laboratory tool for in vitro (outside a living organism) research only. This compound is not for human consumption or any form or in vivo research.
It is the sole responsibility of the purchaser to ensure this compound is legal to purchase and import for research chemical purposes in their country.
This compound is intended to be used in strict laboratory conditions, following all proper precautionary protocol for any novel and untested chemical. The toxicological and physiological action of this compound have not been assessed and so extreme caution should be observed when handling this compound. Please follow proper health and safety guidelines, in a well ventilated and well equipped laboratory when handling this compound.