What is 6-APB?
What is 6-APB used for?
6-APB is used to analyse the binding profile of the receptors it binds to in vitro (outside of a living organism). This means that researchers can determine the affinity, efficacy and duration of action that 6-APB has upon Dopamine, Norepinephrine and Seretonin receptors.
Our 6-APB pellets are produced to make it easier for researchers to have an accurately weighed pellet ready for use, without the need to deal with the open powder and weighing scales. We also pellet this product due to the nature of the chemical and the fact it may be dangerous to handle and could cause serious harm if accidentally spilt and inhaled.
6-APB could be used by chemists for primary reagent testing, and by toxicologists and forensic scientists as a reference sample. 6-APB may be used as a reference sample by analysing it and adding it to the appropriate NMR, HPLC, FTIR or GC/MS library.
Buy 6-APB from ResearchChemicals.biz
We have managed to secure a consistent and trusted supplier of 6-APB powder, with purity that is laboratory grade. We use the same supplier as those who supply the official Benzo Fury resellers. We offer recorded deliver as Standard to ensure you always receive your order. Tracking number issued.
All orders of 6-APB are strictly not for human consumption and must only be used for legitimate research chemical purposes bycustomers over the age of 18.
6-APB – Discovery, History & Research
6-APB was first researched in 1993 by a team lead by David E Nichols at Purdue University, 6-APB then later published in a patent filed in early 1999 and eventually published in August 2000, by Eli Lilly and Company under Patent number 60117385 as part of a research group interested in 5-HT2C agonists.
As one of the first heavily marketed research chemicals, 6-APB was given the informal name “Benzofury” and was first looked at when scientists were studying potentially non-neurotoxic analogues of MDMA. After some pharmacological studies were conducted on its Phamacodynamics and receptor binding affinities most of the other other published research surrounded its subsequent banning around the world, or its toxicology reports. 6-APB was later scheduled in most major western countries from as early as 2009 onwards.
Research into 6-APB began with David E Nichols back in 1993, with some description of its potential as an MDMA analogue with non-neurotoxic attributes. Other than this work, the majority of publications are to do with Toxicology and legal status as a “legal high” or research chemical.
Below you may find some of the more notable publications
6-APB – Chemical Structural Data
6-APB is a synthetic benzofuran molecule with a phenethylamine core as would be expected of most stimulants in it’s family. 6-APB, however, differs in that it has no methyl substitution RN (much like its chemical cousin MDA) however, it has an oxygen-substituted benzofuran ring with a fusion of both R3 and R4 on the phenyl ring. 6-APB is closely related to other research chemical compounds such as -5-APB, 6-MAPB and 5-MAPB.
6-APB – Structure-Activity & Chemical Similarity Predictions
We are lucky to have some actual published data on the pharmacology of 6-APB, showing that it acts as a releasing agent and re-uptake inhibitor and three of the main recreational based protein transporters, serotonin, dopamine and noradrenaline. The following data is available: Kivalues of 117, 150 and 2698 nM for NET, DAT and SERT respectively as well as being a potent agonist for the 5-HT2B receptor (Ki 3.7 nM).
This would give 6-APB the ability to act as a potent stimulant, entactogen and and empathogenic psychoactive.
Key Areas of Research
Samples of 6-APB to purchase online may be used in the following scientific applications.
- As a forensic sample and/or for forensic chemical catalogues
- As a reference sample for Toxicology laboratories.
- As a chemical reagent and/or intermediate
- Pharmaceutical Intermediate
- As a research chemical sample within studying pharmacology of receptor binding assays.
- Affinity and Efficacy Receptor profiling at the DAT, NERT and SERT.
- Reference sample for the application within future therapeutic compounds
- Pure reference standard for chemical analytical libraries using HPLC, FTIR, NMR and GC/MS equipment
6-APB – Online Anecdotal Reports
6-APB has been available in powder and pellet form, to purchase online from research chemicals vendors all over the world, including the USA, UK, Canada and Australia.
Furthermore, the online research chemicals community have taken to forum discussions with questions revolving around 6-APB experience, duration, legal status and dosages. There are some very interesting anecdotal forum where the discussion is in-depth and even talk about 6-APB vendors, in posts on Reddit, Erowid and Psychonaut.
Forum links to anecdotal discussion by those who are able to buy 6-APB powder online.
Chemical Safety, Legality & Indented Use
This is a research chemical compound. Sold as an analytical standard, reagent or laboratory tool for in vitro (outside a living organism) research only. This compound is not for human consumption or any form or in vivo research.
It is the sole responsibility of the purchaser to ensure this compound is legal to purchase and import for research chemical purposes in their country.
This compound is intended to be used in strict laboratory conditions, following all proper precautionary protocol for any novel and untested chemical. The toxicological and physiological action of this compound have not been assessed and so extreme caution should be observed when handling this compound. Please follow proper health and safety guidelines, in a well ventilated and well equipped laboratory when handling this compound.